Organon §255

Even with such patients, a physician will come to closure on the question of amelioration or aggravation by going through the disease image recorded in his case notes, symptom by symptom with the patient, as well as inquiring about any new, unusual ailments.

Amelioration

If a. the patient complains of no new, unusual ailments, b. none of the old befallments has worsened, and c. one has already observed a mental and emotional improvement, then the medicine must also have brought forth an altogether essential decrease of the disease or, if little time has elapsed, it will do so soon. Assuming that the remedy is appropriate, if the visible improvement of the patient is delayed too long, this indicates either some error of conduct on the part of the patient or it indicates that some other circumstances [obstacles to cure] are hindering improvement.

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