In provings with unpotentized medicines, substances of different strengths should be proven in different quantities.*
In medicinal provings, with respect to their actions in the healthy body, one must bear in mind the following:
1. Even in small doses, the strong, so-called heroic substances tend to arouse condition-alterations, even in robust persons.
2. In these experiments, substances of milder power must be administered in more considerable doses.
3. For the action of the weakest medicines to be perceived, they can only be tested upon persons who are free of disease and who are delicate, excitable and sensitive.