Organon §60

When these ill effects are countered with stronger and stronger doses of the antipathic medicine, a more serious disease, or death, results.

When these ill-consequences arise from the antipathic employment of medicines (as may very naturally be expected) the ordinary physician believes he can aid his cause by giving, with each renewed aggravation, a stronger dose of the medicine. This results, likewise, in only a short-lasting pacification. 125 Since this necessitates an ever higher intensification of the palliative, there ensues either another greater malady or frequently even incurability, danger to life, or death itself, but never cure of a malady that is old or very old.