Organon §189

Little cogitation is needed for it to dawn on us that no external malady (except those that arise from particular external damages) can arise without internal causes, can persist in its place or even grow worse, without the cooperation of the entire (consequently, sick) organism. Such external maladies could not come to light at all without the concurrence of the entire rest of the condition and without the participation of the living whole, that is, without the participation of the life principle that governs in all the other sensible and irritable parts of the organism. The emergence of such an external malady will not even allow itself to be thought of apart from its being occasioned by the whole of the mistuned life, so intimately do all the parts of the organism cohere and form an indivisible whole in feelings and functions. Therefore, no eruption on the lips, no whitlow occurs without a previous and simultaneous internal indisposition.