Organon §106

The symptoms that are engendered by each medicine must be observed by giving the the medicine to healthy people.

The entire disease-arousing efficacy of the the individual medicines must be known; that is, all the disease symptoms and condition-alterations that each medicine is especially able to engender in healthy people must first have been observed before one can hope to be able to find and select from among the proven medicines, the apt homeopathic remedy for most of the natural diseases.  

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